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Symbol
Name
ID
Socs3
suppressor of cytokine signaling 3
MGI:1201791
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
abnormal granulocyte differentiation
decreased T cell proliferation
abnormal embryonic erythropoiesis
decreased thymocyte number
enlarged spleen
abnormal blood cell morphology/development
abnormal definitive hematopoiesis
abnormal erythropoiesis
abnormal CD4-positive T cell differentiation
abnormal myelopoiesis
extramedullary hematopoiesis
increased erythrocyte cell number
increased nucleated erythrocyte cell number
increased neutrophil cell number
decreased T cell number
abnormal hematopoietic stem cell morphology
abnormal macrophage physiology
abnormal bone marrow cell physiology
Availability Mouse Genotype
Socs3tm1Jni/Socs3tm1Jni *
Socs3tm1Robb/Socs3tm1Robb
Tg(Lck-Socs3)1Kubo/0
Socs3tm1Wsa/Socs3tm2Wsa
Tg(Vav1-cre)1Awr/0  (conditional)
Socs3tm1Wsa/Socs3tm2Wsa
Lyz2tm1(cre)Ifo/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory